Painful ejaculation may be caused by physiological factors such as frequent sexual intercourse and excessive masturbation, or it may be caused by diseases such as urethritis and seminal vesiculitis. 1. Physiological factors: frequent sexual intercourse, excessive masturbation, when repeated stimulation may lead to long-term congestion of the sexual organs, pain in ejaculation. This kind of situation is a normal phenomenon, when the patient to control the frequency of sexual intercourse, masturbation, after appropriate rest, can be relieved. 2. Urethritis: Urethritis is mainly caused by Chlamydia trachomatis infection, mycoplasma infection and other factors, the patient may appear urethral stinging, painful urination, pain during intercourse or ejaculation, fever and other symptoms, some patients may be accompanied by frequent urination, urinary urgency, urethral itching discomfort. 3. Vesiculitis: Vesiculitis may be caused by urinary tract infection, perineum loss, excessive sex life, frequent masturbation, alcoholism and other factors. Patients may experience symptoms such as localized perineal distension, painful ejaculation, painful urination, and bloody semen. There are many causes of pain when ejaculating, patients can go to the regular hospital, for relevant examination, so as to clarify the cause of the disease.