Childhood leukoplakia is not a very specific name for a disease; there are many diseases involving leukoplakia, some of which disappear on their own, and some of which do not. Therefore, whether or not a child’s white spot will disappear on its own depends on the type of disease it is. If it is an inflammatory hypopigmented spot, such white spots can fade on their own in most cases. In the case of anaplastic nevi and anemic nevi, they do not usually fade on their own. If the white spots are caused by a decrease in melanocytes within the epidermis and thus cannot synthesize enough melanin, such as vitiligo, it is less likely that they will recover on their own in this case. This is because the destruction of melanocytes caused by this disease is often the result of immune factors and requires treatment to restore the number of melanocytes before the level of melanin can be gradually restored, so the possibility of self-recovery is relatively small. Children with low immunity and nutritional deficiencies are more likely to develop white spots, so parents should pay attention to ensuring children’s nutrition and allowing them to do more physical exercise. When white spots are found on children’s bodies, they should be taken to a professional hospital in time for diagnosis to clarify the specific causes in order to provide the right treatment.