Drinking a little alcohol 24 hours after the rabies vaccine is given does not usually significantly affect the effectiveness of the rabies vaccine, but heavy drinking is not recommended. During rabies vaccination, it is necessary to maintain normal immunity to produce rabies antibodies in order to effectively resist rabies virus infection. Therefore, within one month of rabies vaccination, it is important to maintain a normal diet, exercise appropriately and pay attention to moderation to ensure the effectiveness of the rabies vaccine, which is the only effective measure for humans to prevent rabies infection. After receiving the rabies vaccine, it is best not to drink alcohol because alcohol may induce or aggravate the adverse reaction of the vaccine, causing symptoms such as fever, nausea, vomiting, abdominal pain, diarrhea, itching, etc. at the injection site, and it may also affect the immune effect of the vaccine and interfere with the production of antibodies. However, if you only drink a little bit of alcohol occasionally, there are usually no serious consequences. In order to avoid affecting the efficacy of the rabies vaccine, it is necessary to follow the doctor’s instructions to receive the vaccine at regular intervals and quantitatively.