Ms. X, a native of Linyi, gradually developed a “strange disease” from about 5 years ago – her eyes get tired easily, she cannot lift her eyelids and cannot see people. As time passed, her whole body became weak, she had difficulty breathing and eating, and then she developed to the current situation where she can’t even speak. Over the past few years, she has been seeking medical help at many hospitals and has taken a lot of medicine, but she has never seen any improvement. Recently, she was introduced to our department and was diagnosed with “thymoma combined with myasthenia gravis”. After discussing with the patient and her family, we decided to remove the thymoma that had already become diseased. In the past, thymectomy was performed by sternotomy, and the wound was 20-30 cm long, which was very traumatic and slow to recover, and the patient was prone to myasthenia gravis syndrome, which could lead to death. Therefore, the doctor decided to adopt a minimally invasive surgical approach for the patient, with only three small 1.5 cm holes, which has little impact on the patient’s cardiopulmonary function and fast recovery after surgery. The first full thoracoscopic enlarged thymoma resection in the city was performed for the patient. The operation was very successful, removing a 3.5cm*2cm*2.5cm thymoma with surrounding fat. A few days after the operation, the patient’s postoperative wound healed well, symptoms were significantly reduced, and quality of life was significantly improved. The thoracic surgery department has treated nearly 100 patients with thymoma (hyperplasia) combined with myasthenia gravis in recent years with the application of minimally invasive thoracoscopic technology and achieved excellent treatment results. With our advanced technology and rich experience, we are willing to help patients to solve their problems, so that more patients can actually enjoy the gospel brought by the progress of modern medical technology. Myasthenia gravis is an autoimmune disease in which the transmission at the neuromuscular junction is impaired due to the reduction of acetylcholine receptors. It is characterized by fatigue and weakness of local or generalized muscles during activity, which can be relieved by rest or anticholinesterase drugs. The disease can be seen at any age, with a low incidence of 0.5 to 1 per 100,000, but there are two peak periods, one for 20 to 30 years old, which is common in women, often accompanied by thymic hyperplasia; the other for 40 to 50 years old, mostly in men, accompanied by thymoma and other diseases, such as hyperthyroidism and rheumatoid arthritis. Most of them are insidious, and the main symptom is skeletal muscle fatigue after a little activity, which improves after a short rest. The most common symptom is extraocular muscles as the first symptom, followed by the medulla oblongata and limb band muscles, and the most serious is the weakness of respiratory muscles. This is a chronic disease that seriously affects work and life and is difficult to heal on its own. In mild cases, the eyelids droop and the vision is blurred, while in severe cases, it is difficult to eat, walk or even breathe. Studies have shown that myasthenia gravis is closely related to the thymus gland, and most of these patients have thymic hyperplasia or thymoma. The thymus gland is an immune organ in the human body. When a person is born, it is relatively large, and as a person grows, the thymus gland slowly shrinks until it disappears. However, if the thymus gland continues to develop or “refuses to shrink”, some will develop into tumors, when the thymus gland secretes a substance that “eats” a substance used for nerve conduction, resulting in muscle weakness. Therefore, it is essential to solve the thymus problem. Although drug treatment is effective, it requires long-term medication and has a large side effect, and most patients are not cured by conservative drug treatment. Surgical treatment of myasthenia gravis is very satisfactory in both the immediate and long-term results, and surgery has been adopted as the first choice of treatment for myasthenia gravis in developed countries. Although surgical excision of the thymus and anterior mediastinal fat tissue is a reliable method to cure myasthenia gravis, with obvious advantages of good long-term results and high cure rate, the traditional surgical method pioneered by Dr. Blalock requires sawing through the sternum, which is traumatic, painful, and leaves an unsightly longitudinal scar of more than 20 cm in the anterior chest, which is the biggest obstacle for many patients, especially young women, who are afraid to accept surgery. This is the biggest obstacle for many patients, especially young women, who hesitate to undergo surgery. In fact, young female patients should receive surgery as early as possible, because research shows that 86% of patients will eventually develop a generalized type, and surgery within a year of the onset of the disease a Ms. X is a native of Linyi, about 5 years ago, gradually got a “strange disease” – eyes are particularly easy to tired, eyelids can not lift, can not see people. She could not raise her eyelids and could not see well. As time passed, her whole body became weak, she had difficulty breathing and eating, and then she developed to the current situation where she could not even speak. Over the past few years, I have been seeking medical help from many hospitals, and I have taken a lot of medicine, but I have never seen any improvement. Recently, he was diagnosed with “thymoma combined with myasthenia gravis”. After discussing with the patient and his family, it was decided to remove the thymoma that had become diseased. In the past, thymectomy was performed by sternotomy, and the wound was 20-30 cm long, which was very traumatic and slow to recover, and the patient was prone to myasthenia gravis syndrome, which could lead to death. Therefore, the doctor decided to adopt a minimally invasive surgical approach for the patient, with only three small 1.5 cm holes, which has little impact on the patient’s cardiopulmonary function and fast recovery after surgery. The first full thoracoscopic enlarged thymoma resection in the city was performed for the patient. The operation was very successful, removing a 3.5cm*2cm*2.5cm thymoma with surrounding fat. A few days after the operation, the patient’s postoperative wound healed well, symptoms were significantly reduced, and quality of life was significantly improved. In recent years, the Department of Thoracic Surgery has applied minimally invasive thoracoscopic techniques to treat nearly 100 patients with thymoma (hyperplasia) combined with myasthenia gravis and achieved excellent treatment results. With our advanced technology and rich experience, we are willing to help patients to solve their problems, so that more patients can actually enjoy the gospel brought by the progress of modern medical technology. Myasthenia gravis is an autoimmune disease in which the transmission at the neuromuscular junction is impaired due to the reduction of acetylcholine receptors. It is characterized by fatigue and weakness of local or generalized muscles during activity, which can be relieved by rest or anticholinesterase drugs. The disease can be seen at any age, with a low incidence of 0.5 to 1 per 100,000, but there are two peak periods, one for 20 to 30 years old, which is common in women, often accompanied by thymic hyperplasia; the other for 40 to 50 years old, mostly in men, accompanied by thymoma and other diseases, such as hyperthyroidism and rheumatoid arthritis. Most of them are insidious, and the main symptom is skeletal muscle fatigue after a little activity, which improves after a short rest. The most common symptom is extraocular muscles as the first symptom, followed by the medulla oblongata and limb band muscles, and the most serious is the weakness of respiratory muscles. This is a chronic disease that seriously affects work and life and is difficult to heal on its own. In mild cases, the eyelids droop and the vision is blurred, while in severe cases, it is difficult to eat, walk or even breathe. Studies have shown that myasthenia gravis is closely related to the thymus gland, and most of these patients have thymic hyperplasia or thymoma. The thymus gland is an immune organ in the human body. When a person is born, it is relatively large, and as a person grows, the thymus gland slowly shrinks until it disappears. However, if the thymus gland continues to develop or “refuses to shrink”, some will develop into tumors, when the thymus gland secretes a substance that “eats” a substance used for nerve conduction, resulting in muscle weakness. Therefore, it is essential to solve the thymus problem. Although drug treatment is effective, it requires long-term medication and has a large side effect, and most patients are not cured by conservative drug treatment. Surgical treatment of myasthenia gravis is very satisfactory in both the immediate and long-term results, and surgery has been adopted as the first choice of treatment for myasthenia gravis in developed countries. Although surgical excision of the thymus and anterior mediastinal fat tissue is a reliable method to cure myasthenia gravis, with obvious advantages of good long-term results and high cure rate, the traditional surgical method pioneered by Dr. Blalock requires sawing through the sternum, which is traumatic, painful, and leaves an unsightly longitudinal scar of more than 20 cm in the anterior chest, which is the biggest obstacle for many patients, especially young women, who are afraid to accept surgery. This is the biggest obstacle for many patients, especially young women, who hesitate to undergo surgery. In fact, young female patients should receive surgery as early as possible because studies have shown that 86% of patients eventually develop the generalized type, and surgery is most effective within one year of the onset of the disease. The advent of television-assisted thoracoscopy has made it possible for most patients to complete the surgery through three small, concealed, 1 to 2 cm-long incisions under the axilla on one side. With the gradual improvement of surgical techniques, more and more reports support this new procedure. There is now an academic consensus that thoracoscopic surgery has achieved the same results as traditional sternal splitting surgery with significantly less trauma and more concealed and aesthetically pleasing incisions. The results are optimal. The advent of TV-assisted thoracoscopy has allowed most patients to complete the surgery through three small, concealed, 1 to 2 cm-long incisions under the axilla on one side. As the surgical technique has been gradually refined, more and more reports have been published in support of this new procedure. There is now an academic consensus that thoracoscopic surgery has achieved the same results as traditional sternotomy with significantly less trauma and a more concealed and aesthetic incision.