Patient: I suffered from Meniere in ’95. After ineffective treatment with medication, I was injected with gentamicin in ’03, and my vertigo improved, but other symptoms did not improve. I would like to use meniett low pressure pulse therapy instrument to treat my condition. Thank you. Yang Haidi, Department of Otolaryngology, The Second Hospital of Sun Yat-sen University: Meniere’s disease is troublesome to treat and often tends to recur. According to your case, you have used many methods to treat it before, but the effect is poor. What is the frequency of vertigo attacks? If your hearing loss is poor and vertigo is frequent, for example, several times a month, then you can consider vestibular neurotomy as a more thorough treatment. If your hearing is still good and vertigo is not very frequent, you can consider intra-drum injection of methylprednisolone, which does not affect your hearing and has good effect. The treatment with meniett low pressure pulse therapy instrument is a new treatment method, but you need to put a ventilation tube on the tympanic membrane, which is more effective, but it takes longer time, about twice a day, and you need to insist on the treatment for 2~3 months, which is not very convenient if you live far away. So any treatment plan needs to be made according to your actual situation, and it is better to see your information before making it. Patient: Thank you Dr. Yang for your reply. I suffered from Meniere’s disease in ’95 and sudden deafness in my lateral ear (left ear), vertigo, tinnitus and ear congestion in ’97. In 07, he underwent endolymphatic bursa decompression surgery because of the unbearable swelling in the ear, but the result was not good. Now I have almost no hearing in the affected ear, and the tinnitus and swelling are very bad. I was very happy to read your paper on the application of low-pressure pulse therapy for Meniere’s disease on the Internet, and I thought that my disease could be cured again. However, I lost my confidence when you suggested cases of patients with poor or ineffective results after intra-dural injection of Gentamicin or decompression surgery. You suggested methylprednisolone injection, but I was concerned about the side effects because I have diabetes and hepatitis C. Neurotomy, I also considered, but did not dare to make up my mind, the surgery was too risky and the nerves in the brain are dense and important. I have been suffering from headaches since my last surgery, and I am considering intracranial complications, and now I have not found any medication. Anyway, I feel kind and warm when I read your reply, thank you. I wish you good health and happiness. Patient: I live in Dalian city, and a local hospital has started to apply Meniett low pressure pulse therapy instrument to treat Meniere’s disease. I would like to have a reply, thank you very much. Yang Haidi, Department of Otolaryngology, The Second Hospital of Sun Yat-sen University: You can consider the treatment for a period of time, because this treatment method is not traumatic and is an effective treatment method between conservative treatment and surgery. I wish you a speedy recovery.