The survival period of hypothyroidism with thyroid nodules needs to be analyzed according to the condition and treatment, and cannot be generalized, it is recommended to consult a doctor. 1. If hypothyroidism is well controlled, thyroid hormone levels are controlled within normal standards, and the thyroid nodules are confirmed to be benign with no obvious symptoms by thyroid ultrasound and fine needle aspiration cytology. At this time, it usually does not affect the life expectancy, and is no different from normal people, and only requires regular observation. 2. If hypothyroidism is not well controlled, coma with mucous edema may occur, which usually requires prompt medical attention. In addition, if the thyroid nodule is malignant, it is recommended to consult a doctor in time and follow the doctor’s instructions. Patients with abnormal thyroid function accompanied by thyroid nodules are advised to seek treatment under medical supervision.