At the age of 51 with uterine fibroids, the symptoms come back after 5 months of menstruation, which may be a normal phenomenon of perimenopause, or may be caused by dysfunctional uterine bleeding, or may be caused by endometrial cancer, which is caused by different reasons and different treatment methods. 1. Physiological factors: 51-year-old women with fibroids are in perimenopausal period, perimenopausal period may lead to the symptom of menstruation coming back after 5 months, which is a normal phenomenon and does not need special treatment. 2. Dysfunctional uterine bleeding: dysfunctional uterine bleeding can also cause 51-year-old women with uterine fibroids to have the symptom of menstruation after 5 months, which can be treated with progesterone and other drugs. 3. Endometrial cancer: 51-year-old women with uterine fibroids who suffer from endometrial cancer can also have the symptom of menstruation after 5 months, which can be treated by total hysterectomy and bilateral adnexectomy, lymph node dissection, as well as radiotherapy, chemotherapy, and the use of medicines such as medroxyprogesterone, tamoxifen, anastrozole, etc. After eliminating physiological factors, if 51-year-old women with uterine fibroids have the symptom of menstruation after 5 months, they can use medicines such as progesterone to treat the symptom. After excluding physiological factors, if a 51-year-old patient suffering from uterine fibroids has the symptom that her period has come back after five months, it is recommended to consult a doctor in time to find out the cause and ask the doctor to dispose of it.