Irritable bowel syndrome refers to a group of clinical syndromes including abdominal pain, abdominal distension, changes in bowel habits and abnormal stool characteristics, mucus stools, and other manifestations that persist or recur, with examination to exclude organic diseases that can cause these symptoms. This is the most common type of functional bowel disease. It used to be called “colonic dysfunction,” “colonic spasm,” “colonic allergy,” “spastic colitis,” and “mucous colitis. “mucous colitis” and so on. With the accelerated pace of life and changes in diet structure in recent years, the incidence of irritable bowel syndrome due to neurological, psychiatric and infectious factors is on the rise. It causes some disturbance to the quality of life and work. Young and middle-aged people are the high incidence group, among which women have more incidence than men, and mental workers are higher than physical workers. At present, more than half of the patients reported as chronic colitis by colonoscopy in general hospitals are suffering from this disease. Due to the lack of proper understanding of this disease, it is treated repeatedly as colitis. The most important clinical manifestations are abdominal pain and changes in bowel habits and stool properties. The abdominal pain is characterized by relief after defecation or exhaustion. The diarrhea is usually about 3-5 times a day, and the stools are mostly thin and mushy or watery, with mucus but never pus and blood. Some patients have alternating diarrhea and constipation or constipation with difficulty in defecation, with dry, low volume stools in the shape of sheep feces or fine rods, with mucus on the surface. Other gastrointestinal symptoms are often accompanied by abdominal distension or bloating, and there may be a sense of incomplete defecation and defecation embarrassment. A considerable number of patients may have insomnia, anxiety, depression, dizziness, headache and other mental symptoms. Currently, the Rome criteria are mostly used internationally, and the latest Rome 3 criteria were released in 2006. Treatment firstly, we should fully understand the characteristics of the disease and eliminate the tension, which is a benign functional disease with little impact on the body itself and no possibility of deterioration, but affects the quality of life. Secondly, establish good habits and avoid symptom-inducing foods in diet, which varies from person to person. In general, it is advisable to avoid gas-producing foods such as dairy products and soybeans, and high-fiber foods can help improve constipation. For insomnia and anxiety, appropriate sedative drugs can be given. Gastrointestinal antispasmodics such as pivulbromine (Desutex) are used at 50mg 3 times/day. For diarrhea, antidiarrheal drugs are used, and for constipation, symptomatic treatment with laxative drugs. Antidepressants may be used for those with abdominal pain or diarrhea and the above treatments are ineffective and for those with significant psychiatric symptoms. Combination therapy with omeprazole enteric dissolve tablets, glutamate tablets, trimebutine maleate tablets. Intestinal flora regulating drugs such as Bifidobacterium, Lactobacillus and other preparations can correct intestinal flora imbalance and are effective for abdominal distension and diarrhea. Other therapies such as psychotherapy, hypnosis, biofeedback therapy, have been reported to be effective abroad. Chinese medicine has good efficacy in the treatment of this disease. According to the clinical manifestations of this disease, it belongs to the category of “abdominal pain”, “constipation” and “depression evidence” in Chinese medicine. From the point of view of the lesion, although the disease is in the large intestine, it is related to the dysfunction of the liver, spleen, stomach and other internal organs. According to clinical experience, mainly divided into two types of identification symptoms liver depression spleen deficiency type: symptoms see diarrhea want to discharge, after diarrhea pain reduction, belching food less, easy to irritate and good breath, tongue light red coating thin white, pulse thin string. Treatment is to dredge the liver and regulate qi, strengthen the spleen and resolve dampness. The formula is selected from the formula for painful diarrhea and combined with Ginseng and Atractylodes, with 20 grams of Radix Codonopsis, 20-30 grams of fried peony, 10 grams each of fried Atractylodes, Fructus, Citrus, and Magnolia, 6 grams each of Radix et Rhizoma. 30 grams each of Poria, Quasi Yam, 10 grams each of Shengma and Pueraria. Spleen and kidney Yang deficiency type: symptoms are seen in the form of cold limbs cold, cold pain in the abdomen, loose stools, 3-4 times a day, or five times that diarrhea, diarrhea after the abdominal peace, abdominal distension and dull, like warmth and weakness, light tongue and fat, thin white moss, sunken and thin pulse. Treatment is to warm the spleen and kidney, thicken the intestines and stop diarrhea. The formula is Sishen Wan plus or minus, with 12-15g of Radix Codonopsis Pilosulae (or 15-20g of Radix Codonopsis Pilosulae), 10g each of simmered nutmeg, bone fructus, fried Atractylodes Macrocephala, Chebulus Macrocephala and Bacopa monniera, 15-30g each of fried white herbs and Coix seeds, 6-10g of dried ginger, 6g each of roasted licorice, mucuna pruriens and sandy kernel. At present, we use Chinese herbal medicine in combination with Deschutes and intestinal flora regulating drugs in the treatment, and receive very good The therapeutic effect. However, the disease is prone to recurrence, and good living habits and dietary treatment are also the focus of treatment. The last point is that the diagnosis of this disease is mainly based on clinical symptoms, but colonoscopy and other tests are needed to exclude abdominal pain and diarrhea caused by intestinal tumors or inflammation.