Brain pain generally refers to headache, which may be caused by migraine, tension-type headache, cluster headache, etc. Some common colds may also cause headache, and may also be caused by subarachnoid hemorrhage and meningitis. 1. Migraine: Migraine has a certain genetic susceptibility, more common in women, usually unilateral throbbing pain, aggravated by activities, can be shifted from one side of the head to the other, involving the front of the head or the whole head. 2. Tension-type headache: tension-type headache is related to tension, anxiety, irritability and other emotional stress factors, headache is mostly bilateral temporal, frontal-parietal, occipital and (or) the whole head of the oppressive pain, can be accompanied by head band feeling, such as a spell of tightening. 3. Cluster headache: cluster headache is often associated with vascular neurological factors, the pain is located in one side of the periorbital, supraorbital, behind the eyes and temporal region, and it is often a sharp, explosion-like, non-pulsating pain. 4. Cold and flu: patients may have symptoms of headache, in addition, some patients may be accompanied by fever, fever can lead to intracranial vasodilatation, which can also lead to symptoms of headache. 5. Subarachnoid hemorrhage: When subarachnoid hemorrhage occurs, blood flows into the subarachnoid space due to rupture of blood vessels at the base or surface of the brain, which can lead to sudden and severe headache. 6. Meningitis: Meningitis is an acute inflammatory disease of the cerebrospinal membrane caused by various pathogens, and inflammation stimulating the meninges can also lead to headache symptoms. Headache discomfort may also have other causes, please consult the doctor promptly to identify the cause and timely treatment.