What is the difference between levofloxacin and norfloxacin?

The difference between norfloxacin and levofloxacin can be analyzed in terms of antimicrobial spectrum, targeting the site of infection, dosage form and adverse reactions.
1. Different antibacterial spectrum: Norfloxacin only targets aerobic gram-negative bacilli; levofloxacin can target gram-positive and gram-negative bacilli, Mycobacterium tuberculosis and non-tuberculosis bacilli, in addition to mycoplasma, chlamydia and legionella.
2. Different infection sites: Norfloxacin is generally limited to gastrointestinal and urinary tract infections; Levofloxacin can be used for infections in almost every system of the body.
3. Different dosage forms: Norfloxacin is only available in oral dosage form; Levofloxacin is available in oral, intravenous and eye-drop dosage forms.
4. Different adverse reactions: the adverse reactions of norfloxacin are mainly gastrointestinal adverse reactions, such as nausea, vomiting, abdominal pain and diarrhea, etc.; the adverse reactions of levofloxacin are mainly fever, headache, vision loss and pharyngitis.
It is recommended to choose the appropriate drug under the guidance of specialists; in addition, the application of the above drugs have certain risks, and patients need to get the guidance of specialists.