Chronic simple moss, also known as neurodermatitis, is a common chronic inflammatory cutaneous neurological dysfunction skin disease characterized by paroxysmal itching and mossy skin. It is usually treated with topical glucocorticosteroids, and commonly used medications include dianabed cream, tretinoin cream, and so on. Neurodermatitis is mostly related to mental factors, such as mental anxiety, neurosis, insomnia, late night and other factors. Neurodermatitis is characterized by symmetrical episodes, and the main symptoms are itching and mild flaking. Treatment of systemic therapy to control mental symptoms, ensure sleep to improve the immune system, can be appropriate to regulate the autonomic nervous system of drugs, such as vitamin B1, glutamine and so on. Topical medication is mainly glucocorticoids, such as dexamethasone ointment, fluorine easy cream. All of the above drugs should be used in accordance with medical advice. It is recommended that patients go to the hospital in time, after a clear diagnosis, standardized treatment under the guidance of the doctor.