Toothache is recommended to take non-steroidal anti-inflammatory drugs, such as ibuprofen extended-release capsules, diclofenac sodium extended-release tablets, acetaminophen tablets, etc., but these drugs are only a relief effect, some types of toothache, no obvious effect. Non-steroidal anti-inflammatory drugs are mainly anti-inflammatory, analgesic, antipyretic and so on, through the inhibition of prostaglandin synthesis to play a role, usually recommended to be taken after meals, after taking, if no effect, it is recommended to consult a doctor in time. Patients with peptic ulcers should use it with caution. In addition, it should be noted that toothache is mainly divided into toothache caused by diseases of the dental tissues, toothache caused by periodontal tissues and toothache caused by systemic diseases, in which the periodontal tissues caused by toothache to take non-steroidal anti-inflammatory drugs have a certain effect, and the other two are usually no obvious effect. It is recommended that patients with toothache go to the stomatology department of a regular hospital, and be examined by a physician according to the condition, and treated according to the cause of the disease, and do not take medication on their own, so as not to delay the condition.