The recovery of all functions in patients with depression and generalized anxiety disorder to achieve clinical cure and reintegration into society has been the goal pursued by psychiatrists. on March 21, 2015, at the 17th China Psychoneuroscience Conference, experts at the conference talked about how to achieve a true clinical cure through functional improvement. Depression is characterized by high morbidity, relapse, and disability, affecting patients’ mental and physical health, social interaction, occupational ability, and somatic activities, and posing a serious risk to their quality of life and social functioning. An article published in Science showed that 38% of patients with generalized anxiety have moderate to severe impairment of work capacity, with an average of 6.3 days of work loss per month as a result. First, depression-related functioning involves four areas: the ability to take care of oneself in life, the ability to learn to role-play at work, the ability to coordinate interpersonal, family and social relationships, and self-satisfaction with abilities. The DSM-5 emphasizes functioning among the elements in the diagnosis of depression. Symptoms cause clinically significant distress and lead to impairment in social, occupational, or other important functions. It is important to note that impairment of functioning is caused by symptoms and the two are interrelated. The diagnosis of depression must take into account function, and its diagnostic criteria should include symptomatological, functional, and exclusion criteria, as well as duration of illness. the DSM-5 adds other features to the diagnosis of depression, such as depression with anxiety features. Clinical cure of depression requires three goals: complete symptom resolution, non-relapse, and functional recovery. Symptom remission and functional recovery are the main treatment goals. While some reports suggest that symptom remission and functional recovery are independent of each other, Professor Mei believes that the two are interrelated. Healing in the true sense is recovery. Authoritative guidelines also emphasize that the overall treatment goals for generalized anxiety disorder and depression include functional recovery and improving their quality of life to achieve true healing. The main treatment modalities for depression are pharmacotherapy and psychotherapy. The choice of medication is based on three main criteria: evidence-based evidence, patient experience, and the knowledge structure and habits of the physician. Factors that influence the recovery of social functioning include the patient’s personality and social support system, the illness itself, and the treatment. The safety and convenience of the medication affects patient compliance and thus patient consolidation, and the 2013 APA Annual Meeting suggested that attention should be paid to patient treatment preferences or treatment biases. The patient’s social knowledge, coping style, and personality can also affect their social functioning. Both depression and anxiety disorders have functional impairment, and for those with neurological impairment, recovery of symptoms alone does not represent recovery of function. The earlier the treatment takes effect, the faster the functional recovery. In addition, patients with psychological depression and anxiety problems can add psychotherapy after medication, which can speed up the recovery of social function, with higher clinical healing rate and better results.