The red dots on a person with syphilis are usually referred to as a syphilis rash, which is a symptom of stage 2 syphilis. Syphilis is a disease due to the syphilis spirochete, and transmission is mainly through sexual, blood and mother-to-child transmission. Common symptoms include painless ulcers on the genitals and skin lesions. Syphilis rash is one of the skin lesions. Syphilis rash can mimic a variety of skin diseases, and can subside on its own without treatment in a few weeks or months, and the rash is often symmetrically distributed, and can be spread all over the body. If the patient has high-risk behavior, the skin appeared unknown small red spots, it is recommended to improve the syphilis serological examination as soon as possible to clarify the diagnosis, do not diagnose without authorization, so as not to delay the condition.