The itchy, swollen and hardened fingertips may be caused by angioedema, acute eczema and other causes. 1. Angioedema. Due to heredity, exposure to dust, peanuts and other reasons, angioedema, which leads to skin swelling, pain, hardness and other symptoms. 2. Acute eczema. Acute eczema is caused by contact with pollen, dust mites and other allergic substances, leading to allergic reactions in the fingers, resulting in edema, hardness and itching. Serious cases should go to the hospital in time, symptomatic treatment.