If oral squamous carcinoma develops to the advanced stage before death, because it is a tumor of digestive tract, it will cause the patient to have no way to eat, and then there will be serious malnutrition and cachexia, from the appearance of the patient at this time is extremely thin, still skin and bones, very poor mental health, before death will enter into a drowsy state, gradually in the development of light coma, or even deep coma state. In the last stage, the patient will have some serious pain, especially in the 4-5 days before death, and the pain will be more obvious, and there will be new pain every half an hour, and because the location will often invade the surrounding bones, if the whole face has been invaded by the tumor, even fistula, and there will be some serious infection. In the last period of time, there will be multifunctional organ failure, such as a coarse ralescent sound, for example, sounding like a lot of phlegm in the throat, in addition to respiratory and heartbeat changes, such as this nodding breathing, or a rapid and then slow decline in heart rhythm, followed by a drop in blood pressure, very few patients will have a brief improvement in mental and psychiatric accidents before death.