Patients with kidney stones often experience abdominal pain or even colic. The so-called 10-minute rapid pain relief is usually achieved by oral or intravenous infusion of analgesic and antispasmodic drugs, such as intramuscular 654-2 and prednisolone, and those with smaller stones may opt for pharmacological stone removal. However, the time of drug onset and the therapeutic effect of drugs vary from person to person because of the individual’s physical condition, medical condition, and sensitivity to drugs. Usually patients with painful kidney stones are commonly treated with non-steroidal anti-inflammatory analgesic drugs such as diclofenac sodium, indomethacin, aspirin, and opioid analgesics such as morphine, pethidine, brucine, tramadol, etc., combined with antispasmodic drugs such as atropine and scopolamine to diasporate ureteral smooth muscle and relieve spasm and analgesia. Currently alpha1 receptor blockers can also be used to relieve the symptoms of renal colic caused by ureteral spasm. For patients with small stones and mild symptoms, diclofenac sodium, tamsulosin, sodium potassium bicarbonate, sodium bicarbonate, and allopurinol can be tried for stone removal. However, only a few patients are suitable, and most patients need to undergo extracorporeal shock wave lithotripsy, nephrolithotripsy, ureteroscopy lithotripsy, etc. to remove stones. In addition, acupuncture can also be used as an adjunctive treatment, but it should be done under the guidance of a professional TCM doctor. Most patients can obtain a good prognosis with active treatment, but they also need to drink more water, as well as avoid eating a diet containing oxalic acid, such as strong tea, spinach, asparagus, nuts, etc., and a diet high in purines, such as animal offal, beef and mutton, sea fish, etc., which can be done according to the doctor’s guidance.