Jaundice is 16.4mg/dl on the 12th day of life. If breastfeeding jaundice is considered, you can stop breastfeeding, but if it is not breastfeeding jaundice, you don’t need to stop breastfeeding. Due to the special bilirubin metabolism characteristics during the newborn period, such as bilirubin production is relatively high, the body’s ability to metabolize bilirubin is weak, etc., serum bilirubin can increase, jaundice and other symptoms. For 12 days old baby jaundice is 16.4mg/dl can stop breastfeeding, need to be combined with the cause of jaundice to decide, such as specialist assessment and judgment for breast milk jaundice, can suspend breastfeeding, usually jaundice can be in 24 ~ 72 hours to significantly reduce, at the same time need to pay attention to if the newborn for high-risk, need to be carried out if necessary, phototherapy for the reduction of jaundice. These babies can also be seen with cranial hematoma, infections, gastrointestinal surgical diseases, etc., and need to be treated according to the different causes, such as the presence of infections need to be treated with antimicrobial drugs (e.g., cefuroxime). Jaundice caused by gastrointestinal surgical diseases (e.g. congenital biliary atresia) needs to be treated with surgery. It is recommended that these babies be seen by a specialist to assess the cause of jaundice and treat it, rather than stopping breastfeeding on their own.