Hepatitis B mothers who want to have a healthy baby suffer from some precautions to be delivered and are ready for meticulous preparation. 1, married women with hepatitis B should have a serious and comprehensive medical examination before planning to get pregnant to assess their physical status in order to choose the best time to get pregnant. (1) If a woman with hepatitis B is suffering from acute hepatitis B, she can be cured within a few months after proper treatment and reasonable recuperation, when the liver function is back to normal and the hepatitis B virus antigen index has turned negative. The patient can get pregnant after recuperating for a period of time and fully recovering her strength. (2) Patients with chronic hepatitis B should first find out the severity of their disease and then decide whether to get pregnant. If the patient is a virus carrier, the liver function series is always normal in long-term follow-up examinations, and the ultrasound examination does not suggest cirrhosis of the liver, pregnancy can be considered. If the patient is in the active stage of hepatitis B inflammation, with abnormal liver function check, self-conscious fatigue, loss of appetite, abdominal distension, etc., pregnancy should be avoided at this time. Hard pregnancy in the active stage of liver inflammation increases the burden on the body, the liver has to accomplish more work, hepatitis is not easy to recover, but easily leads to heavy hepatitis, which endangers the life of the pregnant woman. In addition, it is also not good for the development and growth of the fetus. Therefore, patients with active hepatitis B should first receive regular treatment, including antiviral and immunomodulatory therapy. It is beneficial for both mother and child to wait until the liver function is normalized and the viral replication index is negative or the replication capacity is reduced before pregnancy. If ultrasound examination reveals that hepatitis has developed to the level of cirrhosis, accompanied by significant thrombocytopenia, hypersplenism and coagulation disorders, it is best not to get pregnant. Patients with chronic hepatitis B with severe extrahepatic systemic manifestations, such as nephropathy and aplastic anemia, should preferably not get pregnant. It is safer for patients with active hepatitis to become pregnant after treatment, with stable disease and normal liver function for more than six months. Those who had a history of pregnancy but terminated it because their liver could not bear it; those with hepatitis B virus infection with obstetrical and gynecological disorders who should not get pregnant, such as those with a history of repeated cesarean deliveries, should not get pregnant. The ability of hepatitis B virus-infected patients to become pregnant is largely determined by the ability of the liver itself to withstand the burden of the entire pregnancy and delivery process. Some people want to wait until the infectiousness of hepatitis B virus is reduced to zero or very low level before they get pregnant, which is not very realistic, blindly waiting, will miss the best time and age to get pregnant; another part of the people are not considering the body’s ability to bear, holding the mentality of trying to get pregnant, which is very dangerous. 2, once pregnant, hepatitis B patients should terminate the use of various drugs with hepatotoxicity, such as antibiotics, anti-tuberculosis drugs, drugs for the treatment of diabetes, etc.. If you have mildly elevated transaminases in the first 3 months of conception and pregnancy, without other obvious discomfort, it is best not to use drugs in order to prevent malformations in the embryo, and only after 6 months of pregnancy can you use some safer enzyme-lowering drugs with caution. The safety of antiviral drugs applied during pregnancy and lactation in women with hepatitis B is not well understood. Plain interferon and pegylated interferon are contraindicated during pregnancy due to their anti-proliferative effects. 3, pregnant women with hepatitis B during pregnancy, the disease may aggravate, manifested as liver function damage is obvious, transaminases, bilirubin rapidly increased, the patient nausea, vomiting, fatigue and weakness, at this time should terminate the pregnancy, and actively carry out liver preservation and antiviral treatment. 4, hepatitis pregnant women’s sex life should pay special attention to moderation, depending on the situation of hepatitis and the size of the pregnancy week to adjust. (1) In the phase of liver function fluctuations, serum glutathione aminotransferase instability or jaundice, etc., sexual life should be prohibited. Sexual intercourse should also be suspended during the recovery period of acute hepatitis and after the relative stability of chronic hepatitis and liver cirrhosis. Simple carriers of hepatitis B virus should not indulge in sexual intercourse either. If you feel tired, lumbago, fatigue, loss of appetite, etc. the day after sexual intercourse, you should pay attention to the adjustment and suspend sexual life. (2) The first three months of pregnancy and the second three months should try to avoid sex, after 36 weeks of pregnancy, should be absolutely prohibited to prevent miscarriage, premature rupture of the fetal membranes and intrauterine infection. (3) Pay attention to the position of sexual intercourse, avoid riding position and flexion position, prevent the male genitalia from penetrating too deep. The husband should be careful to move slowly, not to stimulate the wife’s nipples too much, avoid pressure on the abdomen, and reduce the amount of activity of the pregnant woman. (4) If vaginal bleeding, back pain, habitual abortion, gestational hypertension syndrome, etc. occur, sex should be absolutely prohibited. (5) Pay attention to the hygiene of sexual life, keep the vulva clean before and after sex, and use penis condoms, which can reduce hepatitis B virus infection between husband and wife. 5, hepatitis B mother gave birth to a newborn, immediately after the immunoprophylactic intervention is to stop hepatitis B “from generation to generation” the most important initiative: the newborn born to a hepatitis B virus-positive mother, should be injected with hepatitis B immunoglobulin as soon as possible within 24 hours after birth, preferably within 4 hours after birth, the dose should be ≥ 100 international units, while in 10 micrograms of recombinant yeast or 20 micrograms of Chinese hamster oocyte hepatitis B vaccine at different sites can significantly improve the effect of blocking mother-to-child transmission. The second dose of hepatitis B immunoglobulin can also be administered within 12 hours after birth, followed by a second dose of hepatitis B immunoglobulin 1 month later and a 10 µg recombinant yeast or 20 µg Chinese hamster oocyte hepatitis B vaccine at different sites at the same time, with the second and third doses of hepatitis B vaccine (10 µg recombinant yeast or 20 µg Chinese hamster oocyte hepatitis B vaccine each) administered at 1 and 6 months intervals, respectively. oocyte hepatitis B vaccine. The latter is less convenient than the former, but its protection rate is higher than that of the former. Newborns can receive breastfeeding from hepatitis B virus-positive mothers after administration of hepatitis B immunoglobulin and hepatitis B vaccine within 12 hours of birth.