Uterine fibroid liquefaction is not a change for the better, but the fibroid has undergone degeneration. Uterine fibroid is a common gynecological benign lesion, with the increase of fibroid, peritoneal pressure, vascular blood supply obstruction, which can lead to fibroid degeneration, liquefaction is the myometrial cell liquefaction and necrosis, the localization can form a cystic structure containing liquid, the texture of fibroid will become softer, and there will be a certain tendency of malignant transformation after liquefaction and degeneration, so the condition has not become better, but has become serious. For female patients who are found to have uterine fibroids with liquefied degeneration, it is recommended that they go to the gynecology department of regular hospitals for consultation, and be actively treated by surgery under the guidance of doctors, so as to prevent the disease from further progressing to malignant lesions.