Mean red blood cell hemoglobin content refers to the average amount of hemoglobin contained in each red blood cell. The average red blood cell hemoglobin is calculated as hemoglobin content per liter of blood/number of red blood cells per liter of blood, and the normal value is 27-32 pg. If it is high, it may be macrocytic anemia, and if it is low, it may be microcytic anemia. 1. High: commonly found in macrocytic anemia such as megaloblastic anemia caused by folic acid or vitamin B12 deficiency. 2. Low: Commonly found in small cell anemia such as iron deficiency anemia and anemia with impaired production of pearl proteins. Mean red blood cell hemoglobin content is mostly used for differential diagnosis of specific types of anemia, but it needs to be combined with some other tests to make a definite diagnosis. After the results of the tests such as the average red blood cell hemoglobin content come out, you should see your doctor for a follow-up appointment at the first opportunity, and your doctor will make a comprehensive judgment on whether there is any problem based on the results of the tests.