Multiple lymph nodes in bilateral neck are usually not serious if the lymph node enlargement is caused by inflammation, but more serious if it is caused by tumor metastasis. 1. Inflammation: Lymph node enlargement caused by inflammation is mostly caused by bacterial infection, which is manifested as swollen and painful lymph nodes, and the center of lymph nodes may become pus, only oral antibiotics can be taken, such as cefixime or cephradine, and the course of treatment is usually about 10-14 days. 2. Tumor metastasis: If the lymph nodes in the neck are enlarged due to tumor metastasis, it is mostly seen in thyroid cancer metastasis. At the same time, you can check the thyroid nodules to determine whether they are benign or malignant. If thyroid cancer is considered, total thyroidectomy is needed, and neck lymph node dissection is also required. Patients with multiple lymph nodes in the neck bilaterally should go to the hospital for timely examination and treatment under the guidance of the doctor.