The hazards after pancreaticoduodenectomy are: 1, perioperative period: some patients have life threatening, including bleeding, postoperative liver failure, gastrointestinal fistula, etc.; 2, after perioperative period: physiological function and normal physiological function change, there will be discomfort during the compensation period, including bloating after eating, indigestion, etc.; 3, recurrence: that is, recurrence 3-5 years after surgery, which proves that the tumor is more malignant and exceeds the control of human immunity. It is more harmful in the range; 4. Metastasis: local metastasis includes liver metastasis, omental metastasis, peritoneal metastasis, etc. Distant metastasis includes bone metastasis, which will cause back pain, such as local compression of nerves, which will cause abdominal pain, and brain metastasis, which will even cause increased intracerebral pressure, brain hernia and sudden death.