Condyloma acuminatum (CA), also known as genital warts or venereal warts, is an epidermodysplasia of the skin caused by the human papilloma virus (HPV) and is spread mainly through sexual contact. It is associated with genital, anal, and cervical cancer, and is easily recurring. The general incubation period is 1-8 months, with an average of 3 months. The disease occurs in the coronal sulcus, foreskin, labia majora and minora, vaginal opening, perineum, perineum, cervix, vagina, scrotum, and also in the oral cavity, rectum, and under the breast. The lesions start as small, soft, light red warty papules that gradually increase in size and can be papules, keratotic plaques, papilla-like or cauliflower-like, corkscrew-like redundancies, often with a tip at the root, and some even fuse into larger masses. It is prone to vesicles, oozing and malodorous. The color ranges from pink to off-white. In dry areas the warts are often small, flat papules, in moist areas they tend to be papilla-like or cauliflower-like. Patients are mostly asymptomatic, especially in women. Some patients may have itching, burning pain, painful intercourse and bleeding after intercourse, and women may have increased leucorrhea. The actual fact is that it is easy to diagnose the typical ones, and the atypical ones can be tested for HPVDNA and, if necessary, pathology. Typical condyloma acuminata can be judged by the clinical experience of the specialist and the typical rash of the patient. The actual fact is that you can find a lot of people who have been in the business for a long time, and they’ve been in the business for a long time.
Here you are taught how to self-identify condyloma acuminata with several related conditions.
1, pseudo warts. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The appearance may be due to physiological variation or vaginal Candida albicans, resulting in increased leucorrhea stimulation. Generally, no treatment is needed to keep the area clean and dry and to reduce local stimulation.
2, penile pearl-like papules. The coronal groove of the penis along the edge of the glans, 1-3mm diameter white, skin color or light red pearl-like papules, smooth surface, do not fuse with each other, a row or several rows arranged, long time change is not significant, no conscious symptoms, no history of unclean sexual intercourse, white acetate test is not white. It can last for decades without change, and generally does not require treatment.
3.Sebaceous gland ectopic disease. It occurs in the glans penis, labia mucosa, and oral cavity, and is a yellow pinpoint and corn-sized papule, with no obvious accumulation of skin above the skin surface and no discomfort. It can last for several years without change and generally does not require treatment.
4, Bowen-like papulosis. The damage is located in the male glans, penile stem, female perianal and labia, etc., as multiple small reddish-brown papules, 2-10mm in diameter, can be fused into plaques, mostly seen in sexually active people under 40 years old. Syphilis serologic tests and syphilis spirochetes are negative, and pathologic examination helps to differentiate. It is mainly due to human papillomavirus high-risk type 16 and 18 (HPV16 and 18) infection. The treatment is basically the same as for condyloma acuminata.
5, angiokeratoma. It is usually not necessary to treat, but also available freezing, laser or electrocautery treatment.
6, flat eczema. There is a history of chancre and other syphilis rash damage, dark-field examination can detect syphilis spirochetes, and syphilis serology is positive. The treatment method according to syphilis.
7, infectious molluscum contagiosum.
The surface is smooth and smooth, and the center is concave over time, and the molluscum contagiosum can be squeezed out. The actual fact is that you can use clamp A, also available frozen, laser or electrocautery treatment.
8, hair follicle inflammation. Mainly due to bacterial infection, in the hair more places to appear, such as male mons pubis, scrotum, female mons pubis, the outer labia and perineum and around the anus, for follicular inflammatory papules, self-conscious itching and slight pain, a few days after the self-fading and healing, without scarring. Sometimes there are pus spots on the top of the papules, surrounded by redness and swelling, and hard nodules can be palpated at the base, which are painful and can exist singly or occur simultaneously. Most of the antibiotics are administered orally and locally.
9.Papular syphilis rash. The papules are round, slightly elevated, red to dark red, 2-5mm in diameter or larger, infiltrated to touch, and mostly without conscious symptoms. Circumscribed syphilis rash is commonly found on the pubic area, especially on the penile shaft and scrotum, with a ring-shaped, bow-shaped or gyrate rash, mildly elevated surface with scaly edges, consisting of tiny flat papules, and positive for syphilis seropositivity. Treatment according to syphilis.
10.Seborrheic keratosis. This disease is mostly seen in the middle-aged and elderly, mainly manifested as oval or irregular patches of vulva or papilloma-like projections, the surface covered with oily pale white scab or dry and rough, and normal tissue boundary is clear, no conscious symptoms, generally do not need to deal with, also available freezing, laser or electrocautery treatment, if necessary, surgical treatment.
11, warty xanthoma. Prevalent in the oral cavity, female pubic, penis, scrotum, for yellowish warts damage. Usually no treatment is needed, but it can also be treated by freezing, laser or electrocautery.
12.Genital squamous cell carcinoma. Most often seen in people over 40 years old, often on the basis of the original chronic skin lesions. The damage infiltration is obvious, hard and often forms ulcers. No history of impure sexual intercourse and histopathological examination can be identified. It should be treated surgically and, if necessary, with radiotherapy.
The typical condyloma can be determined by the clinical experience of the specialist and the typical skin rash of the patient. The actual fact is that you can find a number of atypical warts that can be identified by a combination of the following methods
1.White acetate test
2, toluidine orchid test
3, female cervical cytology
4.Immunohistological examination
5.Histopathological examination
6.Dermoscopy
7.HPV-DNA examination
Overview of main treatment methods
1.Electrocautery, laser, freezing or surgery can be used.
2.Local drug treatment can be used 0.5% pediculosis toxin (onychotoxin), 20% pediculosis lipid benzoin tincture, 5% 5-fluorouracil cream or 2-5% 5-fluorouracil solution, 80-90% trichloroacetic acid solution, 3% peptide butylamine cream, 2-8% colchicine solution, paterin solution.
3. Interferon can be injected locally or intramuscularly. It can also be injected intramuscularly with polymyxin, thymidine and BCG.
4, the latest photodynamic therapy is more effective, low recurrence rate, and can treat HPV virus subclinical latent infection lesions, to prevent recurrence.