At present, there is no exact study to show how big the hepatocellular carcinoma is and whether it will definitely show symptoms or not is related to its size, location and whether it has metastasized or not. 1. Size and location. Hepatocellular carcinoma starts insidiously and often has no obvious symptoms in early stage. When the cancer grows gradually and stretches the liver periosteum, the patient may have hidden pain in the upper abdomen; when the cancer presses the gastrointestinal tract, it may be accompanied by nausea and vomiting and other digestive symptoms; when it obviously presses the bile ducts, it may have jaundice and other symptoms of bile obstruction. 2. Whether it is metastasized or not. As a kind of malignant tumor, the symptoms of hepatocellular carcinoma are also related to whether it has distant metastasis and its metastatic site. If no obvious metastasis occurs, local symptoms and systemic malignant symptoms such as fatigue and poor appetite are the main symptoms; if distant metastasis occurs such as metastasis to lungs, symptoms such as coughing and blood in sputum may appear. All in all, the possible symptoms of hepatocellular carcinoma cannot be judged simply according to the size of hepatocellular carcinoma. It is recommended that patients with hepatocellular carcinoma should seek timely medical treatment and standardized diagnosis and treatment in order to get the best prognosis.