Pituitary microadenoma does not disappear automatically. Pituitary microadenoma is a relatively small tumor size, <1 cm, called pituitary microadenoma. Microadenoma certainly will not disappear automatically. If there is no secretory function, you can observe it and just ignore it. If there is a hormone secretion disorder, patients with prolactinoma or adrenal cortex with high secretion function need to be treated with a combination of medication. If there are small lesions, you can also do stereotactic radiation therapy directly, such as the old people think of gamma knife, radio wave knife, hospital TOMO knife, X knife, do treatment can also achieve the same effect as surgery. The pituitary microadenoma will not disappear automatically. Depending on the patient's dangerous progression, if the tumor grows fast, it needs to be treated in time, requiring surgery, drugs or stereotactic radiotherapy intervention. If the growth is slow and the tumor does not move much, the benign tumor can be observed for the presence or absence of secretory function, which does not affect the quality of life. Therefore, pituitary microadenoma will not disappear by itself, but the use of drugs can inhibit the growth and improve the quality of life of the patient.