People have the impression that patients with depression are always sullen, depressed and full of sadness. However, in hospital outpatient clinics, we sometimes encounter depressed patients with smiling faces. They are courteous to the doctor and smile as they talk about their various physical discomforts, such as headache, insomnia, fatigue, abdominal discomfort or pain, loss of appetite, weight loss, loss of libido, impotence, dizziness and swelling, chest tightness or discomfort in the chest area, poor breathing, back pain, nausea and vomiting, constipation, difficulty in urination, etc. Patients often have somatic discomfort as a prominent complaint and believe they are suffering from some kind of physical illness. Some patients, before depression is clearly diagnosed, seek medical treatment everywhere, but they cannot be cured for a long time, and they frequently go to various general hospitals. In fact, it is not that the patient is not depressed, but the physical symptoms are so obvious that the patient only pays attention to the physical symptoms and ignores the depressed state of mind. In clinical work, we call this type of depression “occult depression”. Occult depression accounts for 10%-30% of depression, mostly in the age of 36-64, and is more common in women, about twice as often as in men. Due to the difficulty of identification and lack of targeted treatment, patients suffer from the disease for a long time and are prone to negative behaviors, which cause unnecessary losses to families and society. Therefore, the somatization symptoms of depression should attract our attention more. Patients who are mainly suffering from somatic discomfort and have repeatedly been examined in general hospitals without finding any abnormality should seek help from psychologists in time. The treatment of occult depression is mainly based on antidepressant drugs, together with psychotherapy, which is generally effective after 2 to 4 weeks of medication and can be expected to be cured in 3 to 6 months.