Especially in new patients, when taking a medical history, patients will talk about a rather strange phenomenon, that is, they feel like something is moving inside the wound, for example, they suspect that it is a worm, what is the cause? In fact, this condition is often indicative of the presence of infection and abscesses for diabetic patients, long forming sinus tracts or fistula holes. Experienced doctors can initially confirm the diagnosis from the characteristics of the wound, or by probing with instruments, and for those who do not know or need to do tests to confirm the diagnosis. It is important to observe whether the incision is red, swollen, and painful, and whether there is an increase in temperature. If the temperature is elevated locally, there is a fluctuating feeling of local abscess formation, and the laboratory tests show an increase in white blood cells, which supports abscess formation, it is recommended that surgical incision and drainage be performed. Why does a sinus tract or fistula hole form? This is because there is a risk of rapid spread of inflammatory tissue along blood vessels or tendons and into surrounding tissues following wound infection. I had a particularly severe case of a patient whose infection penetrated along the tendon to the calf there, causing severe damage to the patient. Incision and drainage for thorough debridement is one of the effective methods of treatment, but my advice is to go to a department that specializes in the treatment of diabetic foot to do the surgery, such as our hospital specialty that has a professional stoma therapist to do what is essentially debridement. Some hospitals also use negative pressure drainage to suck out inflammatory tissue, which I personally think is a bit incomplete, and some strongly adherent and sticky necrotic material cannot be cleaned up, resulting in incomplete removal of inflammation. Moreover, in professional departments, they will also take into account the characteristics of difficult wound healing and develop a comprehensive and personalized treatment plan according to the patient’s own situation, so that the situation will not get worse with a clear diagnosis and the cooperation of the patient and family. Finally, I would like to remind you that once you have an abnormality, especially if you have an infected wound that does not heal for a long time, you must find a specialist to treat it in a timely manner to avoid the serious formation of a sinus tract or fistula hole, which can cause serious harm to the patient.