Leprosy vaccine may cause local reaction, mild systemic reaction, severe systemic reaction, etc. It is recommended to consult a doctor immediately when abnormal symptoms occur. 1. Local reaction: redness and mild swelling at the injection site may occur after leprosy vaccination, which generally do not need special treatment and will disappear in one or two days. 2. Mild systemic reaction: Leprosy vaccine may cause fever, fatigue, nausea and other symptoms, and it is recommended to reduce fever and stop vomiting under the guidance of doctors. 3. Severe systemic reaction: after leprosy vaccination, a few patients may have anaphylactic shock, anaphylactic purpura and other symptoms, and it is recommended to consult a doctor immediately to receive treatment. Leprosy vaccine may cause local reaction, mild systemic reaction, severe systemic reaction and other symptoms, and it is recommended to consult a doctor for treatment after abnormal symptoms other than local reaction occur.