Generally uterine fibroids over 5cm should be surgically removed, but also according to the symptoms to decide. Uterine fibroids are the most common benign gynecological tumors, mostly found in women in their childbearing years, and most of them have no obvious symptoms and are merely found during physical examination. However, when the size of fibroid exceeds 5cm, surgical removal is recommended to avoid further development causing symptoms such as excessive menstruation and compression of the vesico-rectal area, etc. Surgery can be performed according to age, fertility requirements, and so on. Fibroid removal surgery can choose transabdominal, transvaginal or laparoscopic surgical resection treatment under doctor’s guidance. After the surgery, it is necessary to pay attention to proper rest, not to carry out physical labor and strenuous exercise too early, keep the vulva clean and dry, and increase the protein-containing food appropriately in order to promote the recovery of the body, and the resected tissues should be sent to the pathology for examination, and follow up the results in a timely manner.