Elderly people with swollen calves need to clarify the cause of the swelling. There are many causes of calf swelling, the common ones are hypoplasia of lower extremity venous valves, chronic kidney disease, liver disease, heart disease and thyroid disease, etc. According to the different causes, different medications and other treatments can be given. In the case of lower limb venous valvular hypoplasia, it is recommended that the patient should not stand for a long time and can wear compression stockings to reduce swelling. If the swelling of calves caused by kidney disease, such as nephrotic syndrome need oral prednisone acetate treatment, some need to use cyclophosphamide and other immune agents. If it is caused by chronic glomerulonephritis need to take astragalus granules and other Chinese medicines, as well as ACEI or ARB antihypertensive drugs treatment. Liver disease and heart disease caused by edema, first of all, the cause of treatment, followed by symptomatic can eat furosemide, spironolactone and other diuretics to reduce swelling treatment. If hypothyroidism causes swelling of the calves, you need to take levothyroxine sodium tablets. All of the above medications should be used under the guidance of a doctor, avoid self-medication.