For patients with paralyzed lower limbs, nursing care is a very professional and arduous task, and whether it can be taken care of well is crucial to the patients’ quality of life. First of all, due to the poor blood circulation of paralyzed lower limbs, it is easy to form pressure sores in the lower limbs, so it is necessary to ensure that the skin is clean, dry, and pay attention to keep warm. Warm water should be used to wash the lower limbs, take good care of urination and defecation, change clothes in time, and keep the living environment clean to reduce the growth of bacteria and avoid the formation of pressure sores. Secondly, the psychological convenience of nursing should be done well, because this kind of patients are easy to lose confidence in life, self-abandonment, need to be correctly guided. So that patients can accept their present self and face up to their life, they should be allowed to do what they can and be a valuable person. Finally, they should also be given enough nutrition, drink more water, and move their lower limbs appropriately to promote the circulation of blood. For patients with lower limb paralysis, not only do they need to do a good job of physical care, they should also do a good job of psychological care.