Pimples on both sides of the temples, usually seen in acne, can be prescribed topical retinoids, benzoyl peroxide, antibiotics and other treatments. 1. Retinoic acid drugs: Retinoic acid can reduce the formation of tiny pimples by inhibiting the differentiation and proliferation of hair follicle epithelial cells. The drug has a slight irritation, can appear tingling, burning sensation and erythema, pay attention to the use of a small area to start the application, and then expand the application if tolerated. Commonly used retinoic acid drugs include retinoic acid ointment, adapalene gel and so on. 2. Antibiotics: common ones include clindamycin, fusidic acid, erythromycin, etc., which can effectively kill Propionibacterium acnes and other anaerobic bacteria, thus reducing the inflammatory response. 3. Benzoyl peroxide gel: Benzoyl peroxide is an oxidizing agent, which can kill Propionibacterium acnes while slowly releasing active oxygen to effectively inhibit inflammation. Its main adverse reactions include local burning sensation, itching, dryness, flaking, and avoid contact with eyes and other mucous membrane areas when applying. There are many topical medications used for the treatment of acne, it is recommended to go to the hospital in a timely manner, according to individual circumstances, under the guidance of the doctor to choose the appropriate treatment drugs.