Renal insufficiency is a relatively serious disease. When renal insufficiency occurs, the ability of the kidneys to excrete water decreases, leading to the accumulation of water in the body, which may lead to swelling of the calves, or the symptoms of facial swelling. If patients with renal insufficiency are not treated in time, as the condition develops, it may lead to an increase in capillary permeability of the glomeruli, which in turn leads to protein leakage and formation of urinary proteins, and hypoproteinemia may occur. Renal failure occurs when the kidneys are damaged for a long time, resulting in toxic substances that cannot be excreted from the body in time, which may lead to uremia in patients. It may even be life threatening, so renal insufficiency is a more serious disease. Patients with renal insufficiency should go to the hospital in time for relevant examinations, and after combining specific symptoms and clarifying the cause of the disease, systematic treatment should be carried out under the guidance of doctors.