Cervical squamous epithelial lesions with glandular involvement are more serious. Cervical squamous epithelial high-grade lesions involving glands is a manifestation of precancerous cervical lesions, lesions are more serious, the condition may be further aggravated by the occurrence of cervical cancer, and need to carry out human papillomavirus test, if positive, you can use ribavirin, recombinant human interferon α-2b vaginal effervescent tablets and other drugs to remove the virus. In addition, cervical conization surgery can be used for treatment, and then 3 months to do colposcopy to check whether the removal is clean and whether there is no recurrence, also need to review the human papillomavirus test again. For patients with high-grade cervical squamous epithelial lesions involving the glands, it is recommended to go to the hospital for timely examination and standardized treatment under the guidance of the doctor.