Anemia does not usually lead to high urea. High urea may be the result of high protein intake for a short period of time; it may also be the result of glomerular injury, including acute renal failure, chronic nephritis, renal arteriosclerosis, chronic pyelonephritis, and renal tuberculosis, which can lead to a decrease in the glomerular filtration capacity, and the patient will experience an elevated urea level. It is also possible that renal tubular reabsorption is enhanced, resulting in increased urea recycling and elevated urea levels. Anemia mainly leads to abnormal red blood cell counts, abnormal hemoglobin concentration, and abnormal mean hemoglobin volume, which usually do not affect urea levels. Therefore, in the event of anemia or high urea, patients are advised to seek prompt medical attention and treatment under the guidance of a physician.