Whether a kidney transplant at 35 years old can live to 70 years old is generally influenced by a combination of immunologic and non-immunologic factors. In the last 20 years, the survival rate of renal transplant patients within 5 years was about 67%, and the 10-year survival rate was less than 38%. For the survival cycle of kidney transplant patients and immune factors (such as immune deficiency, acute rejection, etc.), non-immune factors (such as ischemic time of the transplanted kidney, primary renal disease, hypertension, hyperlipidemia, donor-recipient matching, etc.) are related, and in the last 20 years of medical data, the five-year survival rate of renal transplant patients is about 67%, and the 10-year survival rate is less than 38%. After kidney transplantation, patients need to take immunosuppressive drugs for life, pay attention to observe the urine volume and color, and do regular review. The survival of patients after kidney transplantation depends on many factors and cannot be generalized. It is recommended that patients should develop good living habits and follow up with doctor in time if they feel unwell.