Fetal widening of the lateral ventricles may be caused by occupying lesions, hydrocephalus, and other disorders. Fetal widening of the lateral ventricles may be caused by a space-occupying lesion, and hypoplasia of the corpus callosum may develop during fetal life, usually as a result of congenital causes. Symptoms such as slowed motor and speech development, epilepsy, or cerebral nerve palsy can occur. As far as available treatments are concerned, corpus callosum hypoplasia cannot be changed and can be improved by rehabilitation. Fetal lateral ventricle widening may be caused by hydrocephalus. Hydrocephalus caused by midbrain aqueduct stenosis diaphragm formation after atresia temporalis foramen ovale atresia malformation leads to fetal lateral ventricle widening, which will present with symptoms of gradual enlargement of posterior skull and delayed development of movement, which can be treated by lateral ventricle ventriculoperitoneal shunt surgery. Therefore, the widening of fetal lateral ventricles in the clinic should go to the hospital as soon as possible to clarify the cause of the disease, and actively cooperate with the treatment after diagnosis.