Pharmacologically, megestrol tablets are a semi-synthetic progestin derivative, which has certain inhibitory effect on some hormone-dependent tumors. In clinical practice, megestrol tablets are mainly used to treat advanced breast cancer and advanced endometrial cancer, and also have certain efficacy in kidney cancer, prostate cancer and ovarian cancer, and long-term use of megestrol tablets can improve appetite and cachexia in patients with advanced tumors. The mechanism of action of megestrol tablets may be to control the development and growth of ovarian follicles by affecting the secretion of pituitary gonadotropins, thus reducing the production of estrogen. This drug also acts on estrogen receptors, preventing their synthesis and reuse and interfering with their binding to estrogen, so it can achieve the purpose of inhibiting the growth of hormone-sensitive tumor cells.