Normal people are not recommended to take metformin to lose weight, normal people should achieve weight loss through healthy and reasonable diet, appropriate exercise and other ways. Metformin is a commonly used clinical biguanide glucose-lowering drug, often used as the first-line drug in the treatment of type 2 diabetes mellitus, and can be used alone or in combination with other drugs; combined with insulin may reduce insulin dosage. Adverse reactions such as stomach pain, nausea, vomiting, loss of appetite, diarrhea, weakness, fatigue, dizziness, and skin rash may occur during administration. For the group of simple obesity, weight reduction can be achieved through a healthy lifestyle, such as through reasonable dietary control, appropriate exercise and so on. Specific medication should be administered under the guidance of a specialist, and should not be used without authorization.