There is no such thing as the best oral thrombolytic drug, the current clinical commonly used is the injection type of thrombolytic drugs, mainly atipase and urokinase, streptokinase and so on. Thrombolytic therapy clinically is mainly applied to acute ischemic cerebrovascular disease and cardiovascular disease, as well as cerebrovascular disease patients, generally mainly applicable to cerebral infarction. Urokinase and streptokinase belong to the first generation of thrombolytic agents, which are more widely used thrombolytic drugs in clinical practice. The second generation of tissue-type fibrinogen activator, belonging to the natural thrombus selective fibrinogen activator, such as alteplase can selectively bind with the fibrin on the surface of the thrombus to dissolve the thrombus. The above drugs are for reference only, the specific dosage and usage should follow the doctor’s instructions, not self-medication to avoid adverse reactions.