Uremia is an advanced stage of chronic renal failure, which is essentially severe kidney damage that usually occurs when the kidneys are damaged and lose compensatory function as a result of various chronic kidney diseases. People who are prone to uremia are patients with kidney diseases, patients with kidney-related diseases and people with other kidney injuries. First, patients with kidney disease: 1, patients with hereditary kidney disease: people with family history of hereditary kidney disease are more prone to chronic kidney disease than normal people, such as polycystic kidney, hereditary nephritis, Fabry disease, etc. Chronic kidney disease can easily lead to uremia; 2, patients with primary glomerular disease: patients with primary glomerular disease, especially primary glomerulonephritis, which is not effectively treated for a long time, may cause kidney fibrosis, which is the most common cause of chronic renal failure, thus making it easier for uremia to occur; 3, patients with interstitial renal disease: patients with chronic interstitial renal disease, such as chronic pyelonephritis, with the development of inflammation, renal parenchymal cell function is reduced, which may induce renal failure and easily lead to uremia; 4, patients with renal vascular disease: renal artery embolism or renal vein aneurysm and other renal vascular disease, will make the kidney blood supply is insufficient thus gradually affecting kidney function, which can lead to uremia in serious cases. Second, patients with kidney-related diseases: 1, patients with diabetic nephropathy: poor glycemic control in diabetic patients may cause related complications, such as diabetic nephropathy, which may lead to chronic kidney injury and secondary uremia; 2, patients with hypertension and renal arteriosclerosis: hypertensive patients with long-term high blood pressure leading to sclerosis of the small renal arteries, which can affect the blood supply to the kidneys, leading to renal insufficiency and easy to induce uremia; 3, patients with Hyperuricemia: It can be divided into chronic hyperuricemia nephropathy and acute hyperuricemia nephropathy. In the early stage of chronic phase, it can be manifested as hypoconcentration of renal tubules, which then gradually affects the glomerular filtration function, with a decrease in creatinine clearance and the occurrence of chronic renal failure. In the acute phase, a large amount of uric acid is blocked in the renal tubules by renal excretion, resulting in a sharp decline in glomerular filtration rate, which is manifested as acute renal failure; 4. Patients with immune system diseases: such as lupus nephritis, purpura nephritis, IgA nephropathy, etc., immune complexes gather in the kidney and affect renal function, and long-term disease may also cause uremia. Third, other kidney injury: 1, trauma patients: trauma resulting in kidney contusion or kidney laceration, may cause acute renal failure and uremia; 2, post-transplant patients: kidney transplant rejection, may also lead to a sharp decline in kidney function induced uremia; 3, drug toxicity of the population: some patients due to other chronic disease needs, long-term oral kidney injury caused by Western drugs such as analgesics The patient’s kidneys may be damaged by the use of herbal medicines or Chinese medicines of unknown nephrotoxicity, which may also cause kidney damage, and these people are more prone to uremia than ordinary people. In addition, people who have frequent late nights, long-term overwork, high salt diet and other bad habits of life and diet, the kidney burden is more serious compared to other people, the occurrence of uremic syndrome, will also have a certain impact. Therefore, the above-mentioned people should pay attention to maintain good living habits, such as regular work and rest, work and rest, and diet to control sodium intake.