Infant ventricular septal defects help to grow well by increasing infant nutrition, avoiding respiratory infections and cardiovascular medication, etc., which can improve the rate of self-healing of ventricular septal defects with a diameter of less than 5 millimeters around one year of age. 1. Ventricular septal defect is a common congenital cardiac malformation, most of them are single malformation, if the diameter of the ventricular septal defect is less than 5 millimeters and not accompanied by other malformations, most of the children can heal naturally in their first year of life. 2. Increasing nutrition helps infants’ organ and organ development and strengthens the body’s resistance, so we should patiently feed them high-calorie, nutritionally balanced and easily digested and absorbed food. 3. Respiratory infections can aggravate the burden on the heart and lungs, resulting in increased shunt flow and affecting the closure of the ventricular septal defect. It is important to pay attention to warmth, avoid colds, and consult a doctor for treatment of fever in a timely manner. 4. Cardiovascular medications, such as diuretics and vasodilators, can reduce the cardiac and circulatory load and decrease the shunt of the ventricular septal defect. 5. Ventricular septal defects with a diameter of more than 10 millimeters, subxiphoid and intracristal ventricular septal defects, associated with other intracardiac malformations (e.g., tetralogy of Fallot, transposition of the great arteries, etc.), and very severe clinical symptoms are virtually impossible to heal on their own, and usually require surgery or other treatments. For infants with ventricular septal defects, it is recommended to go to the hospital for further diagnosis and treatment, and to undergo regular checkups.