Adults with molluscum contagiosum are unlikely to get AIDS, molluscum contagiosum and AIDS are two different types of diseases. Molluscum contagiosum, a contagious skin disease caused by the molluscum contagiosum virus infection, is mainly spread through sexual contact in adults. It causes small, shiny, umbilicated pimples the size of a millet on the genitals, perianal area, lower abdomen, pubic bone and other parts of the body. AIDS is a sexually transmitted disease caused by human immunodeficiency virus infection that is mainly characterized by destruction of the body’s immune system. It causes a variety of opportunistic infections and malignant tumors, and is mainly transmitted sexually, by blood, and from mother to child. Adult molluscum contagiosum and AIDS will be sexually transmitted, but the simple molluscum contagiosum is not very likely to get AIDS, is a different pathogen, should be correctly recognized and distinguished.