Do you need treatment for 500+ prolactin?

The normal range of prolactin is 2.1-17.7ng/mL, 2.8-29.2ng/mL for women who are not pregnant, 9.7-208.5ng/mL for women who are pregnant, and 1.8-20.3ng/mL for women who are menopausal. In general, if the value does not exceed 2 times the normal value and there are no associated discomfort, observation and follow-up are sufficient. Prolactin >500ng/mL is more than twice the normal value and therefore requires treatment. Increased prolactin may cause symptoms such as overflow of breast milk, menstrual disorders, and infertility. Prolactin >500ng/mL, if you have irregular menstruation or overflow of breast milk, it is recommended to have a head CT or MRI to check whether the pituitary gland is suffering from pituitary microadenoma. Treatment needs to be based on the size of the pituitary microadenoma. If the pituitary microadenoma is very small and does not cause other symptoms besides high prolactin, including symptoms of pressure on the nerves, or if there are no other obvious symptoms about the nerves, you can choose medication, such as bromocriptine and carmeglin. If the prolactin is high and the pituitary microadenoma is relatively large and even has a compressive effect on the surrounding nerve tissue, then surgery is required to remove the pituitary microadenoma. If a woman’s prolactin is too high, she may also lose the ability of her ovaries to respond to gonadotropins, resulting in a significant decrease in estrogen and progesterone synthesis and low levels of estrogen, making the process of conception difficult and even directly affecting the function of pregnancy and childbirth, which also requires related treatment.