Cough more serious on the 2nd day after taking the medicine may be the medication is not right, the dose of the drug is not enough, etc., but also need to pay attention to the possibility of repeated infections. 1. medication is not symptomatic: there are many reasons for coughing, such as pharyngitis, bronchitis, pneumonia, post-nasal drip syndrome, cough variant asthma, gastroesophageal reflux disease, etc., the cause of the different, the treatment of drugs is different, if the medication is not symptomatic, the treatment of the disease does not have the effect of the disease, may lead to the patient’s coughing medication has no effect on the alleviation of the cough, and even the disease progresses after the cough is even more serious. 2. Insufficient drug dosage: If you don’t strictly follow the doctor’s instructions when taking medication, and take an insufficient dosage of medication, you may not be able to achieve the desired therapeutic effect, which may lead to a more severe cough. 3. Repeated infections: If the patient’s body resistance is relatively poor, taking drugs during the invasion of new pathogens, re-infection, may also lead to worsening cough symptoms. Cough medicine the next day more serious can also be seen in other reasons, it is recommended to go to the hospital in a timely manner, to identify the cause of the disease, follow the doctor’s instructions for treatment, can not be used privately and increase or decrease the amount of medication.