The most dangerous days of alcohol withdrawal are related to the patient’s own history of drinking and the amount of alcohol consumed, and cannot be generalized. If the patient is highly dependent on alcohol, he or she may experience unresponsiveness and dementia at the beginning of withdrawal. Within about 1 week, patients may experience significant withdrawal reactions such as mania, seizures, confusion, and hyperexcitability. This is mainly due to the fact that the patient suppressed his or her nervous system during long-term heavy drinking, and when alcohol intake is suddenly stopped, the suppressed nervous system is over-activated and these symptoms occur. Therefore, the most dangerous time is during the 1-2 week period after quitting alcohol; persistence will be followed by a relatively stable phase. Therefore, patients are advised to adopt a gradual approach to abstaining from alcohol and to consciously and gradually reduce the amount of alcohol consumed to eventually achieve abstinence. For heavy alcoholics, targeted treatment under the guidance of a psychiatrist is recommended.