A burn blister that breaks and keeps oozing can be treated by measures such as skin disinfection, medication and general treatment. 1. Skin disinfection: first of all, keep the wound and the skin around the wound clean and hygienic, use iodophor to routinely disinfect the wound and the surrounding skin every day. 2. Medication: You can use burn moisturizing ointment and other medications externally, which can play the role of astringency. If there is purulent secretion, or elevated blood test, suggesting infection, erythromycin ointment or mupirocin ointment should be given topical application, and systemic antibiotics, such as penicillin, cefazoxime, etc., should be given when necessary. 3. general treatment: keep the skin hygiene, choose loose clothes to reduce friction, while drinking more water, eat more vegetables, timely replenishment of body fluids, do not eat too much greasy food as well as fried pickled products. Scalded blisters broken has been oozing, need to promptly seek medical attention, the drug should be used under the guidance of a professional doctor.