Ankylosing spondylitis is a chronic, progressive, arthropathy with mesial joint involvement, primarily affecting the sacroiliac joints, spinal joints and paravertebral tissues of the pelvis. It mainly affects young men between the ages of 20 and 30, and is rare over the age of 40. The disease is only one tenth as common in women as it is in men, and the disease is mild. Early symptoms are often stiffness or stiffness and pain in the lower back, especially after turning over at night, waking up, or sitting or standing for a long time, but after activity, the stiffness and pain can be improved. In addition to the lumbosacral joints, the disease can involve the thoracic and cervical spine, manifesting as varying degrees of stiffness and pain. Laboratory tests may reveal a significant increase in immunoglobulin and blood sedimentation, and a positive HLA-B27 locus indicates a high-risk group. x-rays are diagnostic, and patients have characteristic sacroiliac joint changes and “bamboo-like” changes in the spine. Aggressive treatment can reduce joint symptoms, preserve joint function, and minimize the occurrence of deformities. In the pain department, in addition to conventional medications, local blocks are very effective in improving symptoms, and acupuncture release is effective in improving spinal mobility in patients with early onset of spinal mobility restriction.