Although lumbar 5 sacral 1 herniated disc closed injection can reduce the patient’s local pain, control inflammation, relieve edema, etc., but the disease itself can not play a therapeutic effect. Lumbar 5 sacral 1 refers to the lumbar vertebrae of the fifth vertebrae and sacral vertebrae of the first vertebrae to form a segment, is the lumbar spine range of motion is relatively large segment, but also more common disc herniation segment. Patients with lumbar 5 sacral 1 herniated discs may experience pain and numbness in the neck and shoulders, thoracic back, lumbar and leg areas, as well as sensory disturbances and incontinence in some severe cases. Sealing injection refers to performing closed needle therapy, which mainly involves injecting a mixture of pain-relieving and hormonal drugs locally to achieve the purpose of anti-inflammatory and analgesic. Patients with lumbar 5 sacral 1 intervertebral disc herniation with sealing may have the effect of reducing pain, controlling inflammation and improving the condition, but there is no therapeutic effect on the disease itself, and its therapeutic effect is relatively poor. Patients can be diagnosed by a doctor and then undergo surgical treatment to improve the condition of the herniated disc and so on. It is recommended that patients pay attention to rest, avoid excessive fatigue, pay attention to monitoring the condition in their life, and should seek medical treatment in time if persistent pain and activity limitation occur.